Name | Gallacetophenone-4-Methyl Ether |
Synonyms | NSC 46636 Gallacetophenone-4-Methyl Ether GALLACETOPHENONE-4-METHYL ETHER GALLACETOPHENONE-4'-METHYL ETHER Gallacetophenone 4-O-methyl ether 4-METHOXY-2,3-DIHYDROXYACETOPHENONE 2',3'-DIHYDROXY-4'-METHOXYACETOPHENONE 1-(2,3-DIHYDROXY-4-METHOXYPHENYL)ETHANONE 2',3'-DIHYDROXY-4'-METHOXYACETOHPENONE, HYDRATE |
CAS | 708-53-2 |
Molecular Formula | C9H10O4 |
Molar Mass | 182.17 |
Density | 1.284±0.06 g/cm3(Predicted) |
Melting Point | 133 °C |
Boling Point | 359.6±42.0 °C(Predicted) |
Appearance | powder to crystal |
Color | Light yellow to Yellow to Green |
pKa | 8.98±0.15(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
MDL | MFCD00180772 |
In vitro study | 2,3-Dihydroxy-4-methoxyacetophenone protects HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC 50 =10.94 μM). 2,3-Dihydroxy-4-methoxyacetophenone inhibits [Ca 2+ ] accumulation in HT22 cells and has antioxidantive activity. |
In vivo study | 2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine. |
biological activity | 2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from c. Paniculata. 2, can improve cognitive function, has the potential for Alzheimer's disease research. |